40. Human SL1 is composed of all of the following except (A) TBP. (B) TAF 30. (C) TAF: 110. (D) TAF163.

41. Which of the following are typical features of transcriptional activators in eukaryotes? (A) transcription-activation domain (B) DNA-binding domain (C) kinase domain (D) transcription-activation domain and DNA-binding domain

42. Predict the effect of blocking GTPase activity by a mutant lacking the GAP gene. Which of the following would be a possible outcome if cells in this mutant are treated with a growth factor? (A) a sustained level of transduction (B) dramatically reduced interaction of the growth factor with the receptor (C) inactivation of MEK (D) dephosphorylation of the growth factor receptor

43. Which of the following is the most common type of histone modification? (A) lysine e-amino methylation (B) serine o-phosphorylation (C) lysine n-phosphorylation (D) histidine n-phosphorylation

II. Short essay questions: Please answer the following question as sufficient as you can. 1. Please compare the process of mRNA translation in prokaryotes and eukaryotes. 

2. Please provide a specific example that utilize the mechanisms of either DNA recombination or transposons to edit genome, such as transgene, transformation, mutagenesis, mosaic clone analysis, gene knockout, gene replacement. In your example, you need to specify the mechanism(s), the feature of DNA sequences, and the enzyme(s) that are applied in this methodology to which organism or cells. If you don't have an example, you may design one. 

3. What is SOS response? 

4. What proteins bind to the telomeres and are presumably involved in forming telomeric heterochromatin in yeast? 

(1)身為輔導教師，與家長溝通需要注意哪些部分？

(2)上述描述，對應哪些相關法規與輔導諮商倫理議題？

(3)輔導教師召開個案會議時，行政協調包含哪些向度？邀請與會的成員與考量為何？

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