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115年 - 115-1 交通部航港局_船員岸上晉升適任性評估筆試測驗_一等大管輪：維修保養與輔機#140585(50題)

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25. Which of the following statement is correct related to general and gene-specific transcription factors in eukaryotes? (A) TATA-box-binding protein (TBP) binds to the minor groove of DNA, bends the consensus TATA DNA, and is required for most members of class I, II and III genes. (B) For RNAP III, TBP is a component of the general transcription factor TFIIIC. (C) The bZIP transcription factors dimerize through a basic domain and bind to target DNA through a leucine zipper. (D) TFIIE and TFIIH are essential for promoter clearance and transcription elongation. (E) The Cys2His2-zinc finger of TFIIIA is composed of an antiparallel beta-sheet followed by an alpha-helix, and the beta-sheet recognizes and binds to specific DNA sequences in the major groove.

24. Which of the following statement is correct in eukaryotic transcription? (A) Yeast Gcn4 controls amino acid metabolism, containing a domain using the basic region to bind to DNA and helix-loop-helix to form a protein dimer. (B) The carboxyl-terminal domain of RNA polymerase is phosphorylated prior to the formation of the initiation complex. (C) By adding of excess acetyltransferase to in vitro transcription assay, it is likely lead to a tighter association of histone with DNA, resulting in reduced transcription. (D) TAF1 of the general transcription factor TFIID is a helicase and a histone acetyltransferase. (E) The high mobility group protein (HMG I(Y)) plays a role in interferon-ẞ (IFN-ẞ) transcription by bending the DNA, causing more activators to bind and interact with each other to enhance transcription.

23. Which of the following is true for eukaryotic Class I and III general transcription factors, except: (A) TFIIIB and TFIIIC are required for all "classical" class III genes. (B) TFIIIC is an assembly factor that helps TFIIIB to bind to a region just upstream of the transcription start site. (C) Human SL1 is an assembly factor that helps the UPE-binding factor of RNA polymerase I to bind to the core promoter element. (D) TFIIIA is a zinc finger protein & is required for transcription of the 5S rRNA genes, but not the tRNA genes. (E) For the class I transcription, human SL1 consists of TATA-binding protein (TBP) and TBP-associated factors (TAFs), which are different from TAFs found in TFIID.

10. Why is a frameshift mutation located at the beginning of a coding region generally more detrimental to protein function than a missense mutation? Briefly explain the reason. (4 pts)

9. You observe that adding DNase to a bacterial culture prevents the bacteria from acquiring a new hereditary trait. Based on this observation, which gene transfer mechanism is occurring (Transformation, Transduction, or Conjugation)? Explain your reasoning. (4 pts)

8. In quantitative PCR (qPCR), why do we focus on the Ct value (Threshold Cycle) rather than the final amount of product at the end of the reaction? (3 pts) Briefly define what the Ct value represents. (3 pts)

警察英文

講師：Terry Tung

簡介：整理各種警察相關英文考題

憲在進行式~(公職憲法)

講師：YK

簡介：本課程將帶您逐一分析重要法條、考點，將易混淆的觀點整理清楚 並透過歷屆試題及其他題目幫您將觀念更加鞏...

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講師：【站僕】摩檸Morning.

簡介：法條相關的試題

荀子／韓非／李斯／孟子／墨子／孔子

描述：「(甲)是(乙)的老師，對人性善惡的看法與(丁)相左；(乙)、(丙)是同學， (乙)喜刑名法術之學，(丙)曾任秦帝...

郵件補償

描述：郵件補償

1

描述：1

20 我國民事訴訟法第 402 條關於外國法院確定裁判之效力，係： (A)採自動承認制度，原則上外國法院確定裁判之效力自動延伸至我國領土 (B)採自動承認制度，原則上不需任何訴訟程序或登記即自動承認其效力，所以外國的原告可以直 接到我國對被告強制執行 (C)採自動承認制度，程序上必須透過強制執行法第 4 條之 1 提起許可宣告執行之訴請求法院承認 與執行 (D)採自動承認制度，僅限於相互外交承認的國家

5 國際法院在 2010 年公布有關科索沃獨立宣言合法性的諮詢意見。關於這份諮詢意見，下列敘述 何者正確？ (A)此諮詢意見係由塞爾維亞向國際法院提出請求而作成 (B)國際法院認為科索沃宣布獨立之行為未違反國際法 (C)國際法院認為人民自決權於殖民地人民範疇外亦適用 (D)國際法院認為其他國家承認科索沃為獨立國家有溯及至宣布獨立之日的效力

26.有關Cattell流體(fluid)智力和晶體(crystallized)智力的說明，下列何者是最適切的？ (A)瑞文氏非文字推理測驗測量的是流體智力 (B)流體智力主要受教育與文化的影響 (C)晶體智力高的人各項領域表現普遍較佳 (D)晶體智力高的人流體智力往往較低

8.下列何者是 T 細胞的正向免疫檢查點(positive immune checkpoint)，屬於活化型受體？ (A)CTLA-4 (B)CD28 (C)PD-1 (D)LAG-3