13. Which of the following pathogenesis is not associated with squamous cell carcinoma of the head and neck?
(A) Infection with high-risk human papillomavirus (HPV)
(B) Smoked tobacco and alcohol
(C) Actinic radiation and pipe smoking
(E) Herpes simplex virus infection
(D) Chewing of betel quid

14. The most common salivary gland tumor is (A) Basal cell adenoma (B) Warthin tumor (C) Oncocytoma(D) Pleomorphic adenoma(E) Ductal papilloma

15.Which of the following statements is not associated with Barrett esophagus?(A)Barrett esophagus can be identified only thorough endoscopy and biopsy(B) It is usually prompted by GERD symptoms(C) Esophageal squamous cell carcinoma t inoma typically arises in the background of Barrett esophagus (D) It is characterized by intestinal metaplasia within the esophageal squamous mucosa (E) It is associated with an increased risk of cance

16.Which of the following risk factors does not belong to peptic ulcer disease? (A) Menetrier disease(B) Helicobacter pylori infection (C) Cigarette use(D) Chronic obstructive pulmonary disease(E) Psychological stress

17. The disease ofthe gastrointestinal tract is typically transmural in(A) Ulcerative colitis (B) Crohn disease (C) Adenocarcinoma (D) Carcinoid tumor (E) Pseudomembranous colitis

18. Which of the following diseases may have occult metastases at the time of diagnosis?(A) Osteochondroma Ostenhlas (B) Osteosarcoma (C) Chondrosarcoma(D) Osteoblastoma(E) Fibrous dysplasia

19. Hyperucicemia may present in patients with(A) Ankylosing spondylitis (B) Mycobacterial arthritis (E) Ganglion cyst (C) Gout(D) Lyme arthritis

20. Which of the followings is NOT TRUE for deep fibromatosis (desmoid tumor)? (A) Large, infiltrative mass(B) Frequently recur (C) Frequently metastasize(D) Do not metastasize (E) So-called aggressive fibromatosis

21. The most common form of skeletal malignancy is(A) Chondrosarcoma(B) Osteosarcoma (C) Synovial sarcoma(D) Ewing sarcoma(E) Metastatic tumors

22. Mesothelioma is not found with(A) Asbestos bodies are found in increased numbers in the lungs of patients with mesothelioma (B) The tumor cells show strong immunoreactivity to TTF-1 protein (C) Mesothelioma is usually associated with extensive pleural effusion and direct invasion (D) The affected lung becomes ensheathed by a thick layer of soft, gelat a soft, gelatinous, grayish pink tumor tissue (E) The most common cytogenetic abnormalities is homozygous deletion of chromosome 9p leading to loss ofthe tumor suppressor gene CDKN2A.

23.Which ofthe following descriptions is NOT TRUE for Marfan syndrome?(A) A disorder of connective tissues, manifested principally by changes in the skeleton, eyes and cardiovascular system(B) Marfan syndrome results from an inherited defect in an extracellular glycoprotein called fibrillin-1. (C) Skeletal abnormalities are the most striking () Skeletal abnormalties are the most striking feature of Marfan syndrome (D) The most characteristic eristic ocular change is bilateral subluxation or dislocation of the lens (ectopia lentis) (E) The most common finding of cardiovascular lesions is aortic valve prolapse

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