38. In the lac operon, which region of the operon does the repressor bind?

(A) Promoter

(B) Operator

(C) CAMP-CRF binding site

(D) +1 start of transcription

39. TFIID is one of the basal transcription factors to bind the promoter during the assembly of the pre-initiation complex, which ofthe following statements about TFIID is FALSE?(A)TFIID distorts the DNA duplex when it binds.(B)TFIID binds the TATA box in promoters.(C)TFIID binds the DNA only after basal transcription factors have bond the promoter region.(D)TFIID binds Inr and DPE elements in promoters.

40. A characteristic of RNA polymerase in humans that is different from bacterial RNA polymerase is(A) that in humans, there are three distinct nuclear RNA polymerases and only one in bacteria.(B) that in bacterial RNA polymerase is directly recruited to the promoter but in human RNA polymerase is recruited to apre-initiation complex.(C) that in human RNA polymerase many additional transcription factors must bind the promoter first before RNA polymerase isrecruited; whereas in bacteria only the sigma factor is required.(D) All the above are characteristics of RNA polymerase that differ between human and bacteria.

1. Which of the following scientists was the first to describe transposon?(A) Mendel; (B) Morgan; (C) McClintock; (D) Miescher; (E) Avery

2. Which of the following enzymes can destroy the RNA in a solution?(A) ribonuclease; (B) trypsin; (C) ATPase; (D) deoxyribonuclease; (E) Kinase.

3. Which of following codons would not be recognized as a stop coden fortranslation?(A) AUG; (B) UĄG; (C) UAA; (D) UGA; (E) none of the choices are correct.

4. Which of following sequences is a palindrome?(A) GAATTC; (B) CTGACT; (C) ATCCTC; (D) GGCCAA; (E) CCTTTC

5. All of the following descriptions is gene participates in activities conditions except (A) A gene is repository of genetic information; (B) A gene can be replicated; (C) A gene can accept occasional changes, or mutation; (D) Genes are fixed in their position on a chromosome. (E) Genes could also be turned on or off due to certain environmental conditions.

6. Which of following descriptions is not correct for transcription? (A) DNA as a template; (B) Four ribonucleoside triphosphates as subtracts; (C) DNA polymerase as enzyme; (D) Phosphodiester bond in the product chain; (E) the product growing chain in 5' to 3' direction.

7. Which of following descriptions is not correct? (A) The prokaryotic mRNA have a special sequence, called a Shine-Dalgarno sequence; (B) A protein called the cap-binding protein binds to the cap and then helps attract ribosome at eukaryotic mRNAs; (C) The initiation codon interacts with a special aminoacyl-tRNA is N-formylmethionyl-tRNA in eukaryote; (D) The enzyme call aminoacyl-tRNA synthetase that play a specific amino acid attach to a specific tRNA; (E) The tRNA contains a 3-bp sequence that pairs with a complementary 3-bp sequence in an mRNA.

8. The cDNA is (A) circular DNA; (B) complementary DNA; (C) central DNA; (D) cloned DNA; (E) cut DNA.

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