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39.有關癌症患者化學治療期間發生細菌感染,在下列何種情況最常見? (A)corticosteroid治療 (B)中性顆粒細胞(neutrophil)計數<500/µL (C)Hb<7 gm/dL (D)體重損失>10%

44.下列何種惡性病最可能以化學治療藥物(chemotherapy)治癒? (A)non-smal cell lung carcinoma (B)colorectal carcinoma (C)seminoma (D)chronic myeloid leukemia

42.關於grade IV astrocytoma(glioblastoma)的敘述,何者錯誤? (A)此疾病預後不佳,平均存活期小於2年 (B)首次治療以手術,接續併用化學治療(temozolomide)及放射治療為主要治療方式 (C)O6-methylguanine-DNA methyltransferase(MGMT)有表現的腫瘤,對於temozolomide的治療較有療效 (D)bevacizumab可用於復發後的病人,此藥物可以減少腫瘤周邊的水腫,也可延長progression-free survival

27. In a hepatocyte under high energy conditions, PFK-1 activity is significantly reduced. A simultaneous increase in which of the following would most effectively overcome this inhibition and reactivate glycolysis? (A) Citrate (B) Fructose-2,6-bisphosphate (C) Glucose-6-phosphate (D) ATP (E) Fatty acids

28. A man taking multiple medications develops drug toxicity. Laboratory analysis reveals impaired Phase I metabolism. Which of the following reactions is most likely deficient in this patient? (A) Hydroxylation by cytochrome P450 (B) Glucuronidation by UDP-glucuronyltransferase (C) Sulfation by sulfotransferase (D) Glutathione conjugation by glutathione S-transferase (E) Acetylation by N-acetyltransferase