3. Which of the following amino acids has more than one chiral carbon?

(A) Val.

(B) Leu.

(C) Ile.

(D) His.

(E) Ser.

4. Which of the following part of antibody molecule is involved in binding to an antigen?(A) Fab.(B) Constant domain.(C) Fc.(D) Heavy chain.(E) Light chain.

5. The reaction GTP GDP + P; is an example of a(n)_____ reaction.(A) homolytic cleavage.(B) internal rearrangement.(C) free radical.(D) group transfer.(E) oxidation/reduction.

6. Oxidation-reduction reactions in biological system always involve:(A) direct participation of oxygen.(B) transfer of electron(s).(C) mitochondria.(D) formation of water.(E) transfer of hydrogens.

7. Consider the reaction A+B → C+D. Which of the following equation regarding the relationship between the free energy change (AG) at any condition and the free energy change (AGº) at standard state is true?(A) AG° = AG+RTin(A/C).(B) AG = AG+RTln(A/C).(C) AG° = AG+RTln(C/A).(D) AG = AG+RTln(C/A).(E) None.

8. Which statement about glycolysis is not true :(A) Conversion of glucose-6-phosphate to fructose-6-phosphate is an isomerization reaction.(B) In the conversion of glucose to pyruvate, only one step actually involve electron transfer.(C) Conversion of glyceraldehyde-3-phosphate to give 1,3-bisphosphoglycerate is an oxidative reaction.(D) Conversion of 2-phosphoglycerate to give phosphoenolpyruvate is an oxidative reaction(E) All of above are true

9. Which statement of citric acid (CA) cycle is true?1. In eukaryotes, CA cycle take places in mitochondrial matrix.2. CA cycle plays roles in both catabolism and anabolism.3. GTP is a direct source of energy produced in the CA cycle.4. All enzymes of the cycle are located in the matrix, except malate dehydrogenase.(A) 1, 2 and 3.(B) 2, 3 and 4.(C) 1, 3 and 4.(D) 1, 2, and 4.(E) All of above are true.

10. In movief of which one of the following statements is not correct?(A) EPA and DHA from oceanic fish could reduce the assault behaviors.(B) The head in sperm whales is largely made up of triacyglycerols and waxes.(C) Luminous jellyfish contain fluorescent dolicols.(D) In starvation, Pi might have plenty of ketone bodies.(E) Dehydration might result in defective secretion of dopamine or serotonin.

11. Which one of the following statements regarding sphingolipid is not correct?(A) Biosynthesis of ceramide shares the same precursor, palmitoyl-CoA, with glycerophospholipid.(B) Serine is a precursor for the biosynthesis of ceramide.(C) Ceramide promotes apoptosis by inducing mitochondrial outer membrane permeabilization.(D) Sphingomyelin is consisted of ceramide and ethanolamine.(E) Glycosphingolipids are major determinants of blood groups.

12. Which one is not a derivative of cholesterol?(A) Cortisol.(B) Testosterone.(C) Arachidonic acid.(D) Bile acid.(E) Vitamin D3.

13. Which one does not regulate the triacyglycerol cycle?(A) Insulin.(B) Glucagon.(C) PEP carboxykinase.(D) Thiazolidinedione.(E) PPARa.

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