40.The mRNA maturation from pre-mRNA in eukaryotes does not need to go through:
(A) splicing
(B) capping
(C) adenylation
(D) glycosylation

41.In the Cori cycle, the liver is primarily responsible for converting lactate from muscle into a substrate which is returned to muscle. This substrate is chiefly: (A) acetyl CoA (B) glucose (C) alanine (D) pyruvate

42.Which eukaryotic RNA polymerase is responsible for mRNA synthesis? (A) RNA polymerase I (B) RNA polymerase II (C) RNA polymerase III (D) RNA polymerase IV

43.What will be the effect of a single base pair deletion in the middle of a DNA sequence coding for a certain protein? (A) A protein with a single amino acid substitution in its center (B) The gene will not be transcribed and no protein will be produced (C) The amino half of the protein will have a normal sequence (D) The carboxyl half of the protein will have a normal sequence

44.NADPH necessary for de novo biosynthesis of fatty acids can be produced directly by action of: (A) glucose 6-phosphate dehydrogenase (B) mitochondrial malate dehydrogenase (C) glyceraldehyde-3-phosphate dehydrogenase (D) lactate dehydrogenase

45.To purify protein rich in Lysine residues, which of the following material should be used? (A) dextran (B) triton X-100 (C) diethylaminoethyl cellulose (D) carboxymethyl cellulose

46.Cancer cells can proliferate indefinitely because they have high: (A) polymerase activity (B) primase activity (C) telomerase activity (D) helicase activity

47.Which of the following fat-soluble vitamins is involved in blood clotting? (A) vitamin A (B) vitamin D (C) vitamin E (D) vitamin K

48.Glycolysis is only partially reversible because of energy barriers at the reactions catalyzed by: (A) hexokinase, triose phosphate isomerase and pyruvate kinase (B) hexokinase, pyruvate dehydrogenase and phosphoenolpyruvate carboxykinase (C) hexokinase, phosphofructokinase, and pyruvate kinase (D) hexokinase, glyceraldehyde 3-phosphate dehydrogenase and pyruvate kinase

49.Which of the following is true about the difference between fatty acid degradation and biosynthesis? (A) Fatty acid degradation is in cytosol while its biosynthesis is in mitochondria (B) Fatty acid degradation starts at carboxyl end while its biosynthesis starts at methyl end (C) The final product for fatty acid degradation is propinyl CoA while the final product for its biosynthesis is acetyl CoA (D) The malonyl-CoA is involved in the fatty acid degradation, but the malonyl-CoA is not involved in its biosynthesis

50.Acetyl-CoA for de novo fatty acid biosynthesis is formed by the energy-dependent cleavage of: (A) pyruvate (B) oxaloacetate (C) citrate (D) α-ketoglutarate

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