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蛋白質化學

食品化學及食品品保技術

生物化學工程

115年 - 新竹數位實中115健康與護理科_答案.pdf#140180(31題)

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25. Which of the following statement is correct related to general and gene-specific transcription factors in eukaryotes? (A) TATA-box-binding protein (TBP) binds to the minor groove of DNA, bends the consensus TATA DNA, and is required for most members of class I, II and III genes. (B) For RNAP III, TBP is a component of the general transcription factor TFIIIC. (C) The bZIP transcription factors dimerize through a basic domain and bind to target DNA through a leucine zipper. (D) TFIIE and TFIIH are essential for promoter clearance and transcription elongation. (E) The Cys2His2-zinc finger of TFIIIA is composed of an antiparallel beta-sheet followed by an alpha-helix, and the beta-sheet recognizes and binds to specific DNA sequences in the major groove.

24. Which of the following statement is correct in eukaryotic transcription? (A) Yeast Gcn4 controls amino acid metabolism, containing a domain using the basic region to bind to DNA and helix-loop-helix to form a protein dimer. (B) The carboxyl-terminal domain of RNA polymerase is phosphorylated prior to the formation of the initiation complex. (C) By adding of excess acetyltransferase to in vitro transcription assay, it is likely lead to a tighter association of histone with DNA, resulting in reduced transcription. (D) TAF1 of the general transcription factor TFIID is a helicase and a histone acetyltransferase. (E) The high mobility group protein (HMG I(Y)) plays a role in interferon-ẞ (IFN-ẞ) transcription by bending the DNA, causing more activators to bind and interact with each other to enhance transcription.

23. Which of the following is true for eukaryotic Class I and III general transcription factors, except: (A) TFIIIB and TFIIIC are required for all "classical" class III genes. (B) TFIIIC is an assembly factor that helps TFIIIB to bind to a region just upstream of the transcription start site. (C) Human SL1 is an assembly factor that helps the UPE-binding factor of RNA polymerase I to bind to the core promoter element. (D) TFIIIA is a zinc finger protein & is required for transcription of the 5S rRNA genes, but not the tRNA genes. (E) For the class I transcription, human SL1 consists of TATA-binding protein (TBP) and TBP-associated factors (TAFs), which are different from TAFs found in TFIID.

10. Why is a frameshift mutation located at the beginning of a coding region generally more detrimental to protein function than a missense mutation? Briefly explain the reason. (4 pts)

9. You observe that adding DNase to a bacterial culture prevents the bacteria from acquiring a new hereditary trait. Based on this observation, which gene transfer mechanism is occurring (Transformation, Transduction, or Conjugation)? Explain your reasoning. (4 pts)

8. In quantitative PCR (qPCR), why do we focus on the Ct value (Threshold Cycle) rather than the final amount of product at the end of the reaction? (3 pts) Briefly define what the Ct value represents. (3 pts)

選修化學Ｉ 題目演練

講師：Kai

簡介：108課綱高二上學期內容，涵蓋氧化還原反應式平衡、化學計量、反應熱、氣體定律、理想氣體方程式、分壓定律...

機械力學

講師：林佳瑩

簡介：●考前補帖《針對國考精選本科目重點筆記》 在機械工程類科中機械力學考科為工程力學考科的基礎，都包含靜...

112年第二次專技 醫事檢驗師 微生物學與臨床微生物學（包括細菌與黴菌）

講師：Feng Ling Yu

簡介：112年第二次專技 醫事檢驗師 微生物學與臨床微生物學（包括細菌與黴菌）解析

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49.依據「職業安全衛生管理辦法」之規定，雇主對高壓氣體特定設備、高壓氣體容器及第一種壓力容 器應每月定期實施檢查一次，下列規定何者錯誤？ (A)本體有無損傷、變形(B)壓力表及溫度計及其他安全裝置有無損傷 (C)平台支架有無嚴重腐蝕(D)配線、配電盤、開關及控制裝置有無異常

20.考試是學生主要的壓力來源之一，面對即將進入國三的學生，國中基本能力測驗是一場不可避免的重大考 試。某國中校長希望在開學之初找出對壓力反應傾向較高的學生，以便協助因應考試壓力。下列測驗何者最 合適？ (A)情境焦慮量表 (B)特質焦慮量表 (C)貝克憂鬱量表(BDI-II) (D)貝克焦慮量表(BAI)

21.如果就心理測驗(psychological testing)和心理衡鑑(psychological assessment)加以比較，下列的敘述中，那一項的敘述是不適切的？ (A)心理測驗是一種工具，而心理衡鑑是解決問題的過程 (B)心理測驗是測量個案的特定心理向度，而心理衡鑑是針對個案的臨床問題做整體的評估 (C)心理測驗的結果較適用於特定個案問題的深入了解，而心理衡鑑的結果較適合於做個別差異比較，反映個案在團體中的相對位置 (D)實施心理測驗可以測量到智力、性向、成就等能力特質，而心理衡鑑關心的不是分數的多寡，而是個案問 題是如何形成的？如何協助個案解決問題？

29 承上題，該都會區每日發生交通事故 4 次（含）以上的機率為何？Pr (X=x)= ，x=0, 1, 2,…, ∞，λ>0 ! (A) 0.353 (B) 0.168 (C) 0.647 (D) 0.832

34.本月因工作量增加，員工有加班，並請了2名臨時工讀生，下列對成本之敘述，何者正確？ (A)員工基本薪水＋加班費屬半變動成本 (B)臨時工讀生屬於半變動成本 (C)臨時工讀生屬於固定成本 (D)員工基本薪水屬變動成本

7.下列細胞激素何者無法幫助肥大細胞的發育與成熟？ (A)IFN-γ (B)IL-3 (C)IL-4 (D)IL-9