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40. A researcher applies a drug that prevents neurotransmitter release from the presynaptic terminal without affecting action potential propagation. Which change would most likely be observed in the postsynaptic cell? (A) Voltage-gated Ca²⁺ channels would remain closed. (B) Ligand-gated ion channels would fail to open. (C) Resting membrane potential would become more positive. (D) Voltage-gated Na⁺ channels would remain permanently inactivated.

39. Which of the following is common to the development of birds and mammals? (A) The formation of an embryonic epiblast and hypoblast (B) The formation of an embryonic trophoblast (C) The formation of an embryonic yolk plug (D) The formation of an embryonic gray crescent

38. Select the pathway that would lead to the activation of cytotoxic T cells. (A) B cell contact antigen → helper T cell is activated → clonal selection occurs (B) body cell becomes infected with a virus → new viral proteins appear → class I MHC molecule-antigen complex displayed on cell surface (C) complement is secreted → B cell contacts antigen → helper T cell activated → cytokines released (D) cytotoxic T cells → class II MHC molecule-antigen complex displayed → cytokines released → cell lysis

10. Why is a frameshift mutation located at the beginning of a coding region generally more detrimental to protein function than a missense mutation? Briefly explain the reason. (4 pts)

9. You observe that adding DNase to a bacterial culture prevents the bacteria from acquiring a new hereditary trait. Based on this observation, which gene transfer mechanism is occurring (Transformation, Transduction, or Conjugation)? Explain your reasoning. (4 pts)

8. In quantitative PCR (qPCR), why do we focus on the Ct value (Threshold Cycle) rather than the final amount of product at the end of the reaction? (3 pts) Briefly define what the Ct value represents. (3 pts)

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40.依規定，車輛頂高機應每幾個月檢查一次，維持其安全性能？ (A)一個月(B)二個月(C)三個月(D)六個月

17 反致制度之本意，最初係為解決何種問題而生？ (A)準據法的積極衝突 (B)準據法的消極衝突 (C)準據法的積極與消極衝突 (D)排除外國法的適用

29.Groth-Marnat(2019)建議解釋症狀檢核表90修訂版(SCL-90- R)的順序是什麼？ (A)整體指數→ 症狀向度→ 症狀程度／題目 (B)症狀向度→症狀程度／題目→整體指數 (C)整體指數→症狀程度／題目→症狀向度 (D)症狀程度／題目→症狀向度→整體指數

30 假設 y 表示 HDL 濃度，x 表示飲酒量。請問直線迴歸方程式為何？ (A) Ŷ = 1.2683 + 0.0101X (B) Ŷ = 1.2683 + 0.0059X (C) Ŷ = 0.0101+ 0.0004X (D) Ŷ = 0.0101+1.2683X

31 有關分析結果的解釋，下列敘述何者正確？ (A)整體的 HDL 平均值是 1.2683 mmol/L (B)皮爾森相關係數（Pearson correlation coefficient）是 0.096 (C)皮爾森相關係數是 0.31 (D)飲酒量和 HDL 的關聯未達到統計上顯著意義

7.有關接受者操作特性曲線(receiver operating characteristic curve, ROC curve)的敘述，下列何者最適 當？ (A)ROC 曲線下面積(area under ROC curve, AUC)可用以診斷準確性之比較 (B)ROC 曲線之 X 軸代表 1-特異性(偽陰性) (C)藉由 ROC 曲線中偽陰性和偽陽性可訂定疾病之發生率 (D)ROC 曲線愈靠近座標圖左下方愈佳